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1

Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways

Moira Sauane, Rahul V. Gopalkrishnan, Irina Lebedeva, Mei Xin Mei, Devanand Sarkar, Zhao-Zhong Su, Dong-Chul Kang, Paul Dent, Sidney Pestka, Paul B. Fisher

Journal:

Journal of Cellular Physiology

Year:

2003

Language:

english

File:

PDF, 404 KB

english, 2003

2

Ceramide plays a prominent role in MDA-7/IL-24-induced cancer-specific apoptosis

Moira Sauane, Zao-zhong Su, Rupesh Dash, Xiang Liu, James S. Norris, Devanand Sarkar, Seok-Geun Lee, Jeremy C. Allegood, Paul Dent, Sarah Spiegel, Paul B. Fisher

Journal:

Journal of Cellular Physiology

Year:

2010

Language:

english

File:

PDF, 398 KB

english, 2010

3

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner

Su, Zao-Zhong, Lebedeva, Irina V, Sarkar, Devanand, Gopalkrishnan, Rahul V, Sauane, Moira, Sigmon, Carter, Yacoub, Adly, Valerie, Kristoffer, Dent, Paul, Fisher, Paul B

Journal:

Year:

2003

Language:

english

File:

PDF, 488 KB

english, 2003

4

Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein

Sauane, Moira, Gopalkrishnan, Rahul V, Choo, Heng-tong, Gupta, Pankaj, Lebedeva, Irina V, Yacoub, Adly, Dent, Paul, Fisher, Paul B

Journal:

Year:

2004

Language:

english

File:

PDF, 454 KB

english, 2004

5

Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells

Su, Zhaozhong, Emdad, Luni, Sauane, Moira, Lebedeva, Irina V, Sarkar, Devanand, Gupta, Pankaj, James, C David, Randolph, Aaron, Valerie, Kirstoffer, Walter, Mark R

Journal:

Year:

2005

Language:

english

File:

PDF, 616 KB

english, 2005

6

OP10.07: Sonoembryology: 3D ultrasound in comparison with human embryo specimens imaged by microscopy magnetic resonance

R. Ximenes, C. Sauan, A. Ximenes, S. Ajzen

Journal:

Ultrasound in Obstetrics & Gynecology

Year:

2010

Language:

english

File:

PDF, 51 KB

english, 2010

7

mda-7/IL-24: Multifunctional cancer-specific apoptosis-inducing cytokine

Pankaj Gupta, Zao-zhong Su, Irina V. Lebedeva, Devanand Sarkar, Moira Sauane, Luni Emdad, Michael A. Bachelor, Steven Grant, David T. Curiel, Paul Dent, Paul B. Fisher

Journal:

Pharmacology & Therapeutics

Year:

2006

Language:

english

File:

PDF, 2.27 MB

english, 2006

8

The development of MDA-7/IL-24 as a cancer therapeutic

Paul Dent, Adly Yacoub, Hossein A. Hamed, Margaret A. Park, Rupesh Dash, Sujit K. Bhutia, Devanand Sarkar, Xiang-Yang Wang, Pankaj Gupta, Luni Emdad, Irina V. Lebedeva, Moira Sauane, Zhao-zhong Su, Mo

Journal:

Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 476 KB

english, 2010

9

Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): Novel gene therapeutic for metastatic melanoma

Paul B. Fisher, Devanand Sarkar, Irina V. Lebedeva, Luni Emdad, Pankaj Gupta, Moira Sauane, Zao-zhong Su, Steven Grant, Paul Dent, David T. Curiel, Neil Senzer, John Nemunaitis

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.79 MB

english, 2007

10

Leukaemia Inhibitory Factor Induces Mitogenesis in Swiss 3T3 Cells and Selective Enhancement via a Variety of Signalling Events

Carolina Schere Levy, Moira Sauane, Philip S. Rudland, Luis Jimenez de Asua

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 113 KB

english, 1997

11

Prostaglandin F2α (PGF2α) Induces Cyclin D1 Expression and DNA Synthesis via Early Signaling Mechanisms in Swiss Mouse 3T3 Cells

Moira Sauane, Laura Correa, Florencia Rogers, Martı&amp, #x0301, n Krasnapolski, Roger Barraclough, Philip S. Rudland, Luis Jiménez de Asúa

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

12

Leukaemia inhibitory factor or Oncostatin M induction of Swiss 3T3 cells does not require mevalonic acid synthesis nor protein isoprenylation to initiate DNA replication

Moira Sauane, Omar A Coso, Sebastián Giulianelli, Adrian N Giráldez, Philip S Rudland, Luis Jimenez de Asua

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 189 KB

english, 2004

13

Cytokine and tumor cell apoptosis inducing activity of mda-7/IL-24

Rahul V Gopalkrishnan, Moira Sauane, Paul B Fisher

Journal:

International Immunopharmacology

Year:

2004

Language:

english

File:

PDF, 998 KB

english, 2004

14

Inhibition of nucleoside diphosphate kinase activity by in vitro phosphorylation by protein kinase CK2 Differential phosphorylation of NDP kinases in HeLa cells in culture

Ricardo M. Biondi, Matthias Engel, Moira Sauane, Cornelius Welter, Olaf-G. Issinger, Luis Jiménez de Asúa, Susana Passeron

Journal:

Year:

1996

Language:

english

File:

PDF, 724 KB

english, 1996

15

MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine

Moira Sauane, Rahul V Gopalkrishnan, Devanand Sarkar, Zao-Zhong Su, Irina V Lebedeva, Paul Dent, Sidney Pestka, Paul B Fisher

Journal:

Cytokine & Growth Factor Reviews

Year:

2003

Language:

english

File:

PDF, 793 KB

english, 2003

16

Melanoma Differentiation Associated Gene-7/Interleukin-24 Promotes Tumor Cell-Specific Apoptosis through Both Secretory and Nonsecretory Pathways

Journal:

Cancer Research

Year:

2004

Language:

english

File:

PDF, 512 KB

english, 2004

17

Sigma 1 Receptor plays a prominent role in IL-24-induced cancer-specific apoptosis

Do, Winchie, Herrera, Cynthia, Mighty, Jason, Shumskaya, Maria, Redenti, Stephen M., Sauane, Moira

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 897 KB

english, 2013

18

Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

Yacoub, A., Park, M. A., Gupta, P., Rahmani, M., Zhang, G., Hamed, H., Hanna, D., Sarkar, D., Lebedeva, I. V., Emdad, L., Sauane, M., Vozhilla, N., Spiegel, S., Koumenis, C., Graf, M., Curiel, D. T.,

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 1.35 MB

english, 2008

19

Sigma 1 Receptor antagonist potentiates the anti-cancer effect of p53 by regulating ER stress, ROS production, Bax levels, and caspase-3 activation

Happy, Mireille, Dejoie, Jordan, Zajac, Cynthia K., Cortez, Briseida, Chakraborty, Karabi, Aderemi, Joseph, Sauane, Moira

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

20

/IL-24: Exploiting Cancer's Achilles' Heel

LEBEDEVA, I, SAUANE, M, GOPALKRISHNAN, R, SARKAR, D, SU, Z, GUPTA, P, NEMUNAITIS, J, CUNNINGHAM, C, YACOUB, A, DENT, P

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 959 KB

english, 2005

21

N-Glycosylation of MDA-7/IL-24 Is Dispensable for Tumor Cell-Specific Apoptosis and "Bystander" Antitumor Activity

Sauane, M., Gupta, P., Lebedeva, I. V., Su, Z.-z., Sarkar, D., Randolph, A., Valerie, K., Gopalkrishnan, R. V., Fisher, P. B.

Journal:

Cancer Research

Year:

2006

Language:

english

File:

PDF, 804 KB

english, 2006

22

Prostate-Derived ETS Factor Is a Mediator of Metastatic Potential through the Inhibition of Migration and Invasion in Breast Cancer

Turner, D. P., Moussa, O., Sauane, M., Fisher, P. B., Watson, D. K.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 613 KB

english, 2007

23

Psychic and Somatic Vulnerability among Professional Women in Argentina as a Result of the Precarization of Labor Linked During the Socioeconomic Crisis

Masseroni, S., Sauane, S.

Journal:

Journal of Developing Societies

Year:

2002

Language:

english

File:

PDF, 108 KB

english, 2002

24

Leukemia Inhibitory Factor Induces DNA Synthesis in Swiss Mouse 3T3 Cells Independently of Cyclin D1 Expression through a Mechanism Involving MEK/ERK1/2 Activation

Dekanty, A., Sauane, M., Cadenas, B., Coluccio, F., Barrio, M., Casala, J., Paciencia, M., Rogers, F., Coso, O. A., Piwien-Pilipuk, G., Rudland, P. S., de Asua, L. J.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 877 KB

english, 2006

25

Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis

Sauane, M., Su, Z.-z., Gupta, P., Lebedeva, I. V., Dent, P., Sarkar, D., Fisher, P. B.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 420 KB

english, 2008

26

Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24

Emdad, Luni, Lebedeva, Irina V., Su, Zhao-zhong, Gupta, Pankaj, Sauane, Moira, Dash, Rupesh, Grant, Steven, Dent, Paul, Curiel, David T., Sarkar, Devanand, Fisher, Paul B.

Journal:

Cancer Biology & Therapy

Year:

2009

Language:

english

File:

PDF, 777 KB

english, 2009

27

Melanoma differentiation associated gene-7 ( mda-7 )/IL-24: a ‘magic bullet’ for cancer therapy?

Sarkar, Devanand, Lebedeva, Irina V, Gupta, Pankaj, Emdad, Luni, Sauane, Moira, Dent, Paul, Curiel, David T, Fisher, Paul B

Journal:

Expert Opinion on Biological Therapy

Year:

2007

Language:

english

File:

PDF, 1.31 MB

english, 2007

28

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) activates caspases in human prostate cancer cells through sigma 1 receptor

Das, Dibash, Persaud, Leah, Dejoie, Jordan, Happy, Mireille, Brannigan, Oliver, De Jesus, Dayenny, Sauane, Moira

Journal:

Biochemical and Biophysical Research Communications

Year:

2016

Language:

english

File:

PDF, 678 KB

english, 2016

29

MDA-7 regulates cell growth and radiosensitivity in vitro of primary (Non-Established) human glioma cells

Yacoub, Adly, Mitchell, Clint, Hong, Young, Gopalkrishnan, Rahul V., Su, Zhao-Zhong, Gupta, Pankaj, Sauane, Moira, Lebedeva, Irina V., Curiel, David T., Mahasreshti, Parameshwar J., Rosenfeld, Myrna R

Journal:

Cancer Biology & Therapy

Year:

2004

Language:

english

File:

PDF, 1008 KB

english, 2004

30

MDA-7/IL-24 as a cancer therapeutic: from bench to bedside

Dent, Paul, Yacoub, Adly, Hamed, Hossein A., Park, Margaret A., Dash, Rupesh, Bhutia, Sujit K., Sarkar, Devanand, Gupta, Pankaj, Emdad, Luni, Lebedeva, Irina V., Sauane, Moira, Su, Zhao-Zhong, Rahmani

Journal:

Anti-Cancer Drugs

Year:

2010

Language:

english

File:

PDF, 158 KB

english, 2010

31

Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina

Unachukwu, Uchenna John, Warren, Alice, Li, Ze, Mishra, Shawn, Zhou, Jing, Sauane, Moira, Lim, Hyungsik, Vazquez, Maribel, Redenti, Stephen

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 3.04 MB

english, 2016

32

eIF2α Phosphorylation Mediates IL24-induced Apoptosis through Inhibition of Translation

Persaud, Leah, Zhong, Xuelin, Alvarado, Giselle, Do, Winchie, Dejoie, Jordan, Zybtseva, Anna, Aktas, Bertal H, Sauane, Moira

Journal:

Molecular Cancer Research

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

33

Translation Control by p53

Kasteri, Justina, Das, Dibash, Zhong, Xuelin, Persaud, Leah, Francis, Ashleigh, Muharam, Hilal, Sauane, Moira

Journal:

Year:

2018

Language:

english

File:

PDF, 571 KB

english, 2018

34

Eukaryotic Translation Initiation Factor 4A Down-Regulation Mediates Interleukin-24-Induced Apoptosis through Inhibition of Translation

Zhong, Xuelin, Persaud, Leah, Muharam, Hilal, Francis, Ashleigh, Das, Dibash, Aktas, Bertal, Sauane, Moira

Journal:

Year:

2018

Language:

english

File:

PDF, 1.69 MB

english, 2018

35

Self-degradable curcumin polymer with anti-cancer activity

O'Connor, N. A., Einbond, L. S., Redenti, S., Sauane, M., Jitianu, A.

Journal:

Journal of Applied Polymer Science

Year:

2018

Language:

english

File:

PDF, 819 KB

english, 2018

36

Mechanism of Action and Applications of Interleukin 24 in Immunotherapy

Persaud, Leah, De Jesus, Dayenny, Brannigan, Oliver, Richiez-Paredes, Maria, Huaman, Jeannette, Alvarado, Giselle, Riker, Linda, Mendez, Gissete, Dejoie, Jordan, Sauane, Moira

Journal:

International Journal of Molecular Sciences

Year:

2016

Language:

english

File:

PDF, 616 KB

english, 2016

37

IL-24 Promotes Apoptosis through cAMP-Dependent PKA Pathways in Human Breast Cancer Cells

Persaud, Leah, Mighty, Jason, Zhong, Xuelin, Francis, Ashleigh, Mendez, Marifer, Muharam, Hilal, Redenti, Stephen, Das, Dibash, Aktas, Bertal, Sauane, Moira

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 3.94 MB

english, 2018

38

MicroRNA-4719 and microRNA-6756-5p Correlate with Castration-Resistant Prostate Cancer Progression through Interleukin-24 Regulation

Das, Dibash, Persaud, Leah, Sauane, Moira

Journal:

Year:

2019

File:

PDF, 13.37 MB

2019

39

mda -7 (IL-24): Signaling and Functional Roles

Sarkar, Devanand, Su, Zao-zhong, Lebedeva, Irina V., Sauane, Moira, Gopalkrishnan, Rahul V., Dent, Paul, Fisher, Paul B.

Journal:

Year:

2002

Language:

english

File:

PDF, 242 KB

english, 2002

40

Management Practices as Capabilities Leading to Superior Performance

Brito, Luiz Artur Ledur, Sauan, Patrícia Kawai

Journal:

BAR Brazilian Administration Review

Year:

2016

Language:

english

File:

PDF, 696 KB

english, 2016

41

Analysis of Adult Neural Retina Extracellular Vesicle Release, RNA Transport and Proteomic Cargo

Mighty, Jason, Zhou, Jing, Benito-Martin, Alberto, Sauma, Sami, Hanna, Samer, Onwumere, Onyekwere, Shi, Cui, Muntzel, Martin, Sauane, Moira, Young, Michael, Molina, Henrik, Cox, Dianne, Redenti, Steph

Journal:

Investigative Opthalmology & Visual Science

Year:

2020

Language:

english

File:

PDF, 1.23 MB

english, 2020

42

Modulation of the Pol II CTD Phosphorylation Code by Rac1 and Cdc42 Small GTPases in Cultured Human Cancer Cells and Its Implication for Developing a Synthetic-Lethal Cancer Therapy

Zhang, Bo, Zhong, Xuelin, Sauane, Moira, Zhao, Yihong, Zheng, Zhi-Liang

Journal:

Year:

2020

File:

PDF, 2.91 MB

2020